Bacterial biosynthesis of abietane-type diterpene ferruginol from glucose
Modular gene expression for heterologous metabolic pathway can be optimized for bacterial biosynthesis. This is the first demonstration of ferruginol production in bacteria. These findings pave the way for further optimization of diterpene biosynthesis through pathway engineering and module integration in bacterial systems.
Authors
- Han Min Woo (ORCID: https://orcid.org/0000-0002-8797-0477)
- Yu Been Heo (ORCID: https://orcid.org/0009-0003-5457-9126)
- Hyun Jeong Lee (ORCID: https://orcid.org/0000-0002-2312-9048)
- Seong‐Eun Kim (ORCID: https://orcid.org/0000-0002-6310-5366)
- Chaeyeon Kim
Institutions
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Microbial Cell Factories
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1186/s12934-025-02691-3
- Citations
- 2
- Primary Topic
- Plant biochemistry and biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Research Foundation of Korea