Clinical insights into heterogeneity of rheumatoid factor negative polyarticular juvenile idiopathic arthritis across the world
Our results confirm the wide heterogeneity of the clinical presentation and outcome of children with RF-negative polyarticular JIA throughout the world. In particular, relevant differences in the onset age were observed across geographic areas. The group of children with early onset polyarthritis, ANA positivity, and risk of uveitis is remarkably frequent in Southern Europe.
Authors
- Maria Trachana (ORCID: https://orcid.org/0000-0003-3454-4172)
- Alessandro Consolaro (ORCID: https://orcid.org/0000-0002-0065-7614)
- Francesca Ridella
- Angelo Ravelli (ORCID: https://orcid.org/0000-0001-9658-0385)
- Pavla Doležalová (ORCID: https://orcid.org/0000-0001-8375-661X)
- Yosef Uziel (ORCID: https://orcid.org/0000-0003-4655-1652)
- Roberta Naddei (ORCID: https://orcid.org/0000-0001-8098-9055)
- Marco Burrone (ORCID: https://orcid.org/0000-0003-2627-0845)
- Ingrīda Rumba-Rozenfelde (ORCID: https://orcid.org/0000-0002-5022-6281)
- Nicolino Ruperto (ORCID: https://orcid.org/0000-0001-8407-7782)
Institutions
- Tel Aviv University (IL)
- Charles University (CZ)
- Aristotle University of Thessaloniki (GR)
- Istituto Giannina Gaslini (IT)
- Meir Medical Center (IL)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- General University Hospital in Prague (CZ)
- University of Naples Federico II (IT)
- University of Genoa (IT)
- University of Latvia (LV)
Publication Details
- Journal
- Pediatric Rheumatology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1186/s12969-025-01072-9
- Citations
- 1
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77