MiR-21-5p-enriched exosomes from hiPSC-derived cardiomyocytes exhibit superior cardiac repair efficacy compared to hiPSC-derived exosomes in a murine MI model
Overall, hiPSC-CM exos could serve as a potent therapeutic agent for myocardial repair, laying the groundwork for future research into exos as a treatment for ischemic heart disease.
Authors
- Dao-Shun Nie
- Jinyan Chen (ORCID: https://orcid.org/0000-0003-4103-7056)
- Yuqing Gong (ORCID: https://orcid.org/0000-0001-6373-5440)
- Jing-jun Jin
- Guoxing Weng (ORCID: https://orcid.org/0000-0003-0463-8418)
- Kun Wang (ORCID: https://orcid.org/0000-0003-1396-6325)
- Bin Lin (ORCID: https://orcid.org/0000-0002-2937-399X)
- Ronghua Liu (ORCID: https://orcid.org/0000-0001-5623-9000)
- Junyong Han (ORCID: https://orcid.org/0009-0000-4467-7628)
Institutions
- Fujian Medical University (CN)
- Fujian Academy of Medical Sciences (CN)
Publication Details
- Journal
- World Journal of Stem Cells
- Published
- 2025-03-19
- DOI
- https://doi.org/10.4252/wjsc.v17.i3.101454
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61