Fat mass and obesity-associated protein in mesenchymal stem cells inhibits osteoclastogenesis <i>via</i> lnc NORAD/miR-4284 axis in ankylosing spondylitis
This study revealed elevated FTO levels in AS-MSCs and found that FTO regulated the ability of AS-MSCs to inhibit osteoclast formation through the long noncoding RNA NORAD/miR-4284 axis.
Authors
- Pengfei Ji (ORCID: https://orcid.org/0000-0001-5390-460X)
- Quanfeng Li (ORCID: https://orcid.org/0000-0003-0299-7150)
- Jikai Jin
- Zihao Yuan
- Pei Feng (ORCID: https://orcid.org/0000-0003-0400-2110)
- Jiaxin Wang (ORCID: https://orcid.org/0000-0002-6868-6809)
- Yibin Zhang (ORCID: https://orcid.org/0000-0003-0894-9256)
- Peng Wang (ORCID: https://orcid.org/0000-0002-0102-4544)
- Wenjie Liu (ORCID: https://orcid.org/0000-0002-8044-5338)
- Huiyong Shen (ORCID: https://orcid.org/0000-0002-4317-3468)
- Yanfeng Wu (ORCID: https://orcid.org/0000-0001-6409-821X)
- Yunhui Zhang (ORCID: https://orcid.org/0000-0001-9971-0528)
Institutions
- Sun Yat-sen University (CN)
- Eighth Affiliated Hospital of Sun Yat-sen University
Publication Details
- Journal
- World Journal of Stem Cells
- Published
- 2025-03-19
- DOI
- https://doi.org/10.4252/wjsc.v17.i3.98911
- Citations
- 2
- Primary Topic
- Bone and Joint Diseases
- Type
- article
- Field-Weighted Citation Impact
- 3.44