Regulation of lncRNA-ENST on Myc-mediated mitochondrial apoptosis in mesenchymal stem cells: <i>In vitro</i> evidence implicated for acute lung injury therapeutic potential
Our <i>in vitro</i> results show that enhanced lncRNA ENST expression can promote BMSC proliferation and viability by modulating the miR-539/c-MYC axis, reduce apoptosis and induce autophagy, which has suggested its therapeutic potential in the treatment of ALI.
Authors
- Yifeng Shen (ORCID: https://orcid.org/0000-0002-3298-6682)
- G. Yang
- Xuejun Wang (ORCID: https://orcid.org/0000-0001-9267-1343)
- Yu-Song Wang
- Qimin Ma
Institutions
- Shanghai East Hospital (CN)
Publication Details
- Journal
- World Journal of Stem Cells
- Published
- 2025-03-19
- DOI
- https://doi.org/10.4252/wjsc.v17.i3.100079
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87