<scp>HIV</scp>‐negative primary effusion lymphoma: a series of seven cases

PEL can arise in immunocompetent, older patients, in this series all men, and behaves aggressively. These neoplasms are similar to their HIV-positive counterparts with anaplastic cytomorphology, HHV8 infection and a plasmablastic immunophenotype. The aetiology of PEL is uncertain, but may be related to physiological immunodeficiency associated with ageing.

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Publication Details

Journal
Histopathology
Published
2025-03-19
DOI
https://doi.org/10.1111/his.15446
Primary Topic
Viral-associated cancers and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

HIV‐negative primary effusion lymphoma: a series of seven cases

L. Jeffrey Medeiros, Bipin Thingujam, Kung‐Chao Chang, Shu‐hsien Wang et al.
Histopathology
Viral-associated cancers and disorders
article

HIV‐negative primary effusion lymphoma: a series of seven cases

L. Jeffrey Medeiros, Bipin Thingujam, Kung‐Chao Chang, Shu‐hsien Wang, Chang‐Yao Chu, Hao Cheng, Yaping Chen
article en

Abstract

PEL can arise in immunocompetent, older patients, in this series all men, and behaves aggressively. These neoplasms are similar to their HIV-positive counterparts with anaplastic cytomorphology, HHV8 infection and a plasmablastic immunophenotype. The aetiology of PEL is uncertain, but may be related to physiological immunodeficiency associated with ageing.

HistopathologyVol. 87(3)
The University of Texas MD Anderson Cancer Center (US), National Sun Yat-sen University (TW), Kaohsiung Medical University (TW), Chi Mei Medical Center (TW), National Cheng Kung University Hospital (TW)
Good health and well-being
Openalex Percentile: Top 93%
Viral-associated cancers and disorders
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<scp>HIV</scp>‐negative primary effusion lymphoma: a series of seven cases — L. Jeffrey Medeiros, Bipin Thingujam, et al. · Histopathology (2025) | TGRS Research Map | TGRS