Impact of Chronic Preoperative Gabapentinoid Exposure on Surgical and Patient-Reported Outcome Measures Following Lumbar Fusion
Despite compelling basic science literature suggesting gabapentinoid exposure hindering bone health and healing capacity, the current investigation did not find an increase in surgical revision or other adverse outcomes, including opioid use and PROMs, associated with chronic preoperative gabapentinoid use.
Authors
- Gregory Douglas Schroeder (ORCID: https://orcid.org/0000-0002-8895-1964)
- David M. Kaye (ORCID: https://orcid.org/0000-0003-4058-0372)
- José A. Canseco (ORCID: https://orcid.org/0000-0002-2152-5725)
- Chloe Herczeg
- Christopher K. Kepler (ORCID: https://orcid.org/0000-0002-0996-4346)
- Mark F. Kurd (ORCID: https://orcid.org/0000-0001-9680-1088)
- Siddharth Singh (ORCID: https://orcid.org/0000-0002-2640-7269)
- John J. Mangan (ORCID: https://orcid.org/0000-0003-4408-1036)
- Rajkishen Narayanan (ORCID: https://orcid.org/0000-0002-2921-3857)
- Rachel Huang (ORCID: https://orcid.org/0000-0002-7683-8702)
- Alan S. Hilibrand (ORCID: https://orcid.org/0000-0001-8811-9687)
- Alec M Giakas (ORCID: https://orcid.org/0000-0002-0082-1648)
- Alexander Rowan Charlton
- Jeremy C. Heard (ORCID: https://orcid.org/0000-0001-5181-3966)
- Robert J. Oris (ORCID: https://orcid.org/0000-0001-8743-0860)
- Jeffrey A. Rihn (ORCID: https://orcid.org/0000-0002-0423-3675)
- Jonathan Dalton (ORCID: https://orcid.org/0000-0002-7452-2712)
- Michael Carter (ORCID: https://orcid.org/0000-0001-8423-6747)
- Daniel Thomas (ORCID: https://orcid.org/0000-0003-4295-9765)
- Alexander R. Vaccaro (ORCID: https://orcid.org/0000-0002-8073-0796)
- Evgeniy V. Uvarov
Institutions
- Thomas Jefferson University Hospital (US)
- Rothman Orthopaedics (US)
Publication Details
- Journal
- Spine
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1097/brs.0000000000005338
- Primary Topic
- Opioid Use Disorder Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00