Prevalence of High Titre Anti-A and Anti-B Haemolysins Amongst Blood Group “O” Voluntary Donors at Mbale Regional Blood Bank, Eastern Uganda

There is a high proportion of blood group O donors having high titers of anti-A and anti-B (dangerous group O donors), with the most raised antibody being anti-A, which compromises the quality and safety of the blood products. We recommend screening for high-titer anti-A and anti-B antibodies in all blood group O donated units to make them safe for transfusion to non-group O recipients, especially where large volumes of plasma are required.

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Publication Details

Journal
Journal of Blood Medicine
Published
2025-03-01
DOI
https://doi.org/10.2147/jbm.s473771
Citations
1
Primary Topic
Blood groups and transfusion
Type
article
Field-Weighted Citation Impact
1.77
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article

Prevalence of High Titre Anti-A and Anti-B Haemolysins Amongst Blood Group “O” Voluntary Donors at Mbale Regional Blood Bank, Eastern Uganda

Yona Mbalibulha, Enoch Muwanguzi, Benson Okongo, Grace Otekat et al.
1 citations
Journal of Blood Medicine
Blood groups and transfusion
1.77
article

Prevalence of High Titre Anti-A and Anti-B Haemolysins Amongst Blood Group “O” Voluntary Donors at Mbale Regional Blood Bank, Eastern Uganda

Yona Mbalibulha, Enoch Muwanguzi, Benson Okongo, Grace Otekat, Robert Wagubi, Patrick Wabuyi, Ahmed Bumba
article en
1 citations

Abstract

There is a high proportion of blood group O donors having high titers of anti-A and anti-B (dangerous group O donors), with the most raised antibody being anti-A, which compromises the quality and safety of the blood products. We recommend screening for high-titer anti-A and anti-B antibodies in all blood group O donated units to make them safe for transfusion to non-group O recipients, especially where large volumes of plasma are required.

Journal of Blood MedicineVol. Volume 16
Mbarara University of Science and Technology (UG), Mbale Hospital (UG), Mbarara National Referral Hospital (UG), Uganda Blood Transfusion Service (UG)
Openalex Percentile: Top 18%
Blood groups and transfusion
1.77
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Prevalence of High Titre Anti-A and Anti-B Haemolysins Amongst Blood Group “O” Voluntary Donors at Mbale Regional Blood Bank, Eastern Uganda — Yona Mbalibulha, Enoch Muwanguzi, et al. · Journal of Blood Medicine (2025) | TGRS Research Map | TGRS