Micro-nanoscale Bioactive Glass: Functionalized Design and Angiogenic Skin Regeneration

Bioactive glass (BG) is an important class of amorphous inorganic biomaterials, which has been clinically used in hard tissue repair for many years, exhibiting unique tissue repair activity.Recent studies have found that BG also shows effective repair activity in soft tissue, demonstrating significant application potential.Compared with traditional BG, micro-nanoscale bioactive glass (MNBG) has a unique micro-nano structure, which not only retains its excellent chemical composition but also has a larger specific surface area and higher reactivity.These special structures and properties enable MNBG to exhibit significant application potential in promoting vascularization and skin repair/regeneration.This work focuses on the research progress of MNBG in regulating vascularization and skin regeneration, including the abilities of MNBG to promote vascularization and regulate