Cutaneous Evaluation of Fe3O4 Nanoparticles: An Assessment Based on 2D and 3D Human Epidermis Models Under Standard and UV Conditions
The present results indicate significant differences in toxicity between the two in vitro models under UV conditions, highlighting the importance of model selection and exposure parameters in assessing NP safety. Thus, our findings suggest that Fe<sub>3</sub>O<sub>4</sub> NPs may pose some risks under specific environmental conditions, within the limitations of the experimental setup, and further research is needed to refine safety guidelines.
Authors
- Elena-Alina Moacă (ORCID: https://orcid.org/0000-0002-2631-7028)
- Cristina Dehelean (ORCID: https://orcid.org/0000-0002-5482-7092)
- Claudia Watz (ORCID: https://orcid.org/0000-0002-2498-4732)
- Ioana Zinuca Pavel (ORCID: https://orcid.org/0000-0002-2223-5228)
- Felicia Loghin (ORCID: https://orcid.org/0000-0002-4620-2498)
- Mirela F. Nicolov (ORCID: https://orcid.org/0000-0002-8152-5583)
- Andreea Cioca (ORCID: https://orcid.org/0000-0003-2215-6666)
- Lenuța Maria Șuta
- Lavinia Krauss Maldea
- Ioan-Ovidiu Sîrbu
Institutions
- Iuliu Hațieganu University of Medicine and Pharmacy (RO)
- Victor Babeș University of Medicine and Pharmacy Timișoara (RO)
- Romanian Academy (RO)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/ijn.s513423
- Citations
- 2
- Primary Topic
- Skin Protection and Aging
- Type
- article
- Field-Weighted Citation Impact
- 4.01