Metformin as a disease-modifying therapy in osteoarthritis: bridging metabolism and joint health
Metformin effectively alleviates osteoarthritis symptoms and improves metabolic health in patients with both OA and IGT. Further research is needed to explore its long-term effects on joint health, inflammatory markers, and its potential role in OA management in patients without IGT.
Authors
- Iryna Halabitska (ORCID: https://orcid.org/0000-0002-9028-7230)
- Oleksandr Kamyshnyi (ORCID: https://orcid.org/0000-0003-3141-4436)
- Pavlo Petakh (ORCID: https://orcid.org/0000-0002-0860-4445)
Institutions
- I.Horbachevsky Ternopil National Medical University (UA)
- Uzhhorod National University (UA)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.3389/fphar.2025.1567544
- Citations
- 8
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 13.34