Suppression of skin lesions and SLE nephritis by increasing Treg in MRL/FASlpr mice by administration of bee venom Apitoxin®
Overall, the results confirmed that Apitoxin<sup>®</sup> induced clinical improvement in SLE by increasing the proportion of Treg cells and decreasing anti-dsDNA antibodies in the blood, which resulted in therapeutic effects on glomerulonephritis associated with decreased renal infiltration of immune complexes.
Authors
- Duk-Yeon Cho (ORCID: https://orcid.org/0000-0002-4569-1728)
- Young Mo Kang (ORCID: https://orcid.org/0000-0002-7409-0729)
- Sang-Ho Seol
Institutions
- Songdo Hospital (KR)
- National Institute of Ecology (IN)
Publication Details
- Journal
- Advances in Rheumatology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1186/s42358-025-00448-5
- Citations
- 2
- Primary Topic
- Healthcare and Venom Research
- Type
- article
- Field-Weighted Citation Impact
- 2.79