The Impact of Personalized Dietary Interventions on Glycemic Control and Quality of Life in Middle-Aged Adults with Type 2 Diabetes and Co-occurring Depression

Type 2 diabetes (T2D) and depression often co-occur, significantly impacting the health and quality of life (QoL) of middle-aged adults. Personalized dietary interventions, which consider individual metabolic needs and comorbid conditions, offer a promising approach to managing both glycemic control and depression. This review explored the potential of personalized dietary strategies in improving glycemic control and QoL in this population. Personalized dietary plans, including nutrient-rich, anti-inflammatory foods and low-glycemic index diets, have been shown to stabilize blood glucose levels, enhance insulin sensitivity, and alleviate depressive symptoms. By addressing both the physiological and psychological aspects of health, these interventions foster improved self-management behaviors and an overall better QoL. However, challenges such as socio-economic factors, cultural preferences, and adherence to diet persist. The methodology employed in this article involved a systematic review of recent studies that assessed the combined effects of personalized dietary interventions on both glycemic control and mental health in adults with T2D and depression. Personalized dietary approaches not only regulate blood glucose levels but also offer mental health benefits by improving mood and cognitive function. Further research on long-term outcomes is essential to establish the sustainability and broad applicability of these interventions in diverse populations. Keywords: Personalized Dietary Interventions, Type 2 Diabetes, Glycemic Control, Depression, Quality of Life.