COMPARATIVE STUDY ON SYMPTOMATIC TREATMENT IN MÈNIÈRE'S WITH DIURETICS AND WITHOUT DIURETICS

Mènière's disease (MD) is a non-lethal and non-communicable inner ear disorder characterized by tinnitus, episodic vertigo, uctuating sensorineural hearing loss and aural fullness. With an incidence of 15.6 cases per 100,000 among the Indian population [1]. Different treatments have been tried ranges from low-salt diet to betahistine, steroids and diuretics for acute attacks and surgical procedures in refractory cases. Aim: · To evaluate the effectiveness of diuretics in patients diagnosed with MD. Methodology: 50 patients with diagnosed with MD based on clinical history were enrolled in the study between August 2022 to August 2024. 25 patients (Group A) were treated with Tab Furosemide 40mg 1-0-0 orally + Tab Deazacort 6mg 1-1-1 orally + Tab Cinnarizine 20mg + Dimenhydrinate 40mg combination 1-0-1 orally for 10 days and 25 patients (Group B) were treated with Tab Deazacort 6mg 1-1-1 orally + Tab Cinnarizine 20mg + Dimenhydrinate 40mg combination 1-0-1 orally for 10 days. Vertigo episodes, dizziness handicap inventory (DHI) score, tinnitus handicap inventory (THI) scale were compared pre intervention and post intervention after 10 days. Results: Both groups had improvements in DHI and THI scores post treatment. The post-treatment the mean difference in total DHI scores and emotional domain scores were statistically better in Group A. However, there was no signicant difference in mean difference of THI scores between Group Aand Group B. Conclusion: In patients with unilateral MD, both Group Aand Group B were effective in relieving symptoms. Neither group showed signicant changes in hearing levels during this period. However, Group A with diuretics exhibited greater improvements in overall DHI scores and DHI emotional scores compared to Group B.