Bio-Inspired Consecutive Photocatalyzed C–H Nitration of Arenes
Concerned with traditional nitration methods requiring high temperatures, strong acids, or oxidizing agents, we developed an acid-free, selective photocatalytic nitration method using riboflavin tetraacetate and Fe(NO<sub>3</sub>)<sub>3</sub>·9H<sub>2</sub>O under visible light. This method efficiently nitrates various arenes and bioactive molecules with high selectivity and functional group tolerance, offering a sustainable alternative to traditional nitration techniques.
Authors
- Da-Lie An
- Qinghai Shu (ORCID: https://orcid.org/0000-0002-2818-0491)
- Xukai Zhou (ORCID: https://orcid.org/0000-0003-0053-5075)
- Manman Wang (ORCID: https://orcid.org/0000-0002-8089-095X)
- Chao Xu (ORCID: https://orcid.org/0000-0002-1630-6253)
Institutions
- Beijing Institute of Technology (CN)
- Dalian Institute of Chemical Physics (CN)
- Chinese Academy of Sciences (CN)
- Institute of Catalysis and Petrochemistry (RU)
- Biobase (Germany) (DE)
- Qingdao Institute of Bioenergy and Bioprocess Technology (CN)
- University of Chinese Academy of Sciences (CN)
- State Key Laboratory of Catalysis
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1021/acs.joc.5c00024
- Citations
- 5
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 4.68
Funders
- National Natural Science Foundation of China
- Chinese Academy of Sciences
- State Key Laboratory of Catalysis
- Dalian Institute of Chemical Physics