Evaluation of the androgen receptor in patients with ERα-positive early breast cancer treated with adjuvant tamoxifen ± fluoxymesterone

Our findings suggest that an AR-agonist may be of value in AR-enriched, ER-enriched breast cancers and should be studied in future trials because of the availability of new, more tolerable AR-agonists.

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Publication Details

Journal
Breast Cancer Research
Published
2025-03-19
DOI
https://doi.org/10.1186/s13058-025-01992-0
Primary Topic
Estrogen and related hormone effects
Type
article
Field-Weighted Citation Impact
0.00

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article

Evaluation of the androgen receptor in patients with ERα-positive early breast cancer treated with adjuvant tamoxifen ± fluoxymesterone

Matthew P. Goetz, Marie R. Passow, Jordan D. Campbell, Vera J. Suman et al.
Breast Cancer Research
Estrogen and related hormone effects
article

Evaluation of the androgen receptor in patients with ERα-positive early breast cancer treated with adjuvant tamoxifen ± fluoxymesterone

Matthew P. Goetz, Marie R. Passow, Jordan D. Campbell, Vera J. Suman, James N. Ingle, Liewei Wang, Malvika Solanki
article en

Abstract

Our findings suggest that an AR-agonist may be of value in AR-enriched, ER-enriched breast cancers and should be studied in future trials because of the availability of new, more tolerable AR-agonists.

Breast Cancer ResearchVol. 27(1)
Mayo Clinic (US), Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US)
Breast Cancer Research Foundation, George M. Eisenberg Foundation for Charities, Max-Planck-Gesellschaft, National Institutes of Health
Good health and well-being
Openalex Percentile: Top 93%
Estrogen and related hormone effects
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