A Case Report of a 61-Year-Old Woman With Jaundice and Cholelithiasis Presenting With Autoimmune Hepatitis

Autoimmune hepatitis (AIH) is a complex disease with a chronic cell-mediated immunologic process against healthy liver cells. The clinical presentation can vary since the exact cause of AIH is multifactorial. Here, we report a case of a 61-year-old woman with a past medical history of post-traumatic stress disorder and hypothyroidism who presented clinically with diffuse abdominal distention, nausea, vomiting, jaundice, rash on the torso and legs, and tea-burnt orange urine. The patient underwent an initial workup with a complete blood count (CBC), comprehensive metabolic panel (CMP), and gamma-glutamyl transpeptidase (GGT), with results leading towards a mixed intra- and extrahepatic process. This report will show various findings related to AIH to improve the detection and treatment of these patients early on.

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Publication Details

Journal
Cureus
Published
2025-03-19
DOI
https://doi.org/10.7759/cureus.80829
Primary Topic
Liver Diseases and Immunity
Type
article
Field-Weighted Citation Impact
0.00
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article

A Case Report of a 61-Year-Old Woman With Jaundice and Cholelithiasis Presenting With Autoimmune Hepatitis

Nicholas P Michalakis, Muhammad Awais, Archit Patel
Cureus
Liver Diseases and Immunity
article

A Case Report of a 61-Year-Old Woman With Jaundice and Cholelithiasis Presenting With Autoimmune Hepatitis

Nicholas P Michalakis, Muhammad Awais, Archit Patel
article en

Abstract

Autoimmune hepatitis (AIH) is a complex disease with a chronic cell-mediated immunologic process against healthy liver cells. The clinical presentation can vary since the exact cause of AIH is multifactorial. Here, we report a case of a 61-year-old woman with a past medical history of post-traumatic stress disorder and hypothyroidism who presented clinically with diffuse abdominal distention, nausea, vomiting, jaundice, rash on the torso and legs, and tea-burnt orange urine. The patient underwent an initial workup with a complete blood count (CBC), comprehensive metabolic panel (CMP), and gamma-glutamyl transpeptidase (GGT), with results leading towards a mixed intra- and extrahepatic process. This report will show various findings related to AIH to improve the detection and treatment of these patients early on.

CureusVol. 17(3)
Navicent Health (US)
Good health and well-being
Openalex Percentile: Top 93%
Liver Diseases and Immunity
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