DR5 Disulfide Bonding Functions as a Sensor and Effector of Protein Folding Stress
Extreme ER stress triggers triage of transmembrane receptor production, whereby mitogenic receptors are downregulated and death receptors are simultaneously elevated.
Authors
- Olga A. Guryanova (ORCID: https://orcid.org/0000-0002-6514-8466)
- Gregory P. Takacs (ORCID: https://orcid.org/0000-0001-8415-432X)
- Ronald K. Castellano (ORCID: https://orcid.org/0000-0003-4322-9932)
- Brian K. Law (ORCID: https://orcid.org/0000-0002-8411-6531)
- Jeffrey K. Harrison (ORCID: https://orcid.org/0000-0002-1080-5721)
- Zaafir M. Dulloo
- Mary E. Law (ORCID: https://orcid.org/0000-0002-6625-0534)
- Mengxiong Wang (ORCID: https://orcid.org/0000-0002-8290-151X)
- Boaz Tirosh (ORCID: https://orcid.org/0000-0001-8067-6577)
- Raju S. Kanumuri (ORCID: https://orcid.org/0000-0002-6087-6587)
- Brian Hardy
- Grace M. Alexandrow
- Young Il Lee (ORCID: https://orcid.org/0000-0003-4993-9038)
- Abhisheak Sharma (ORCID: https://orcid.org/0000-0003-0553-4039)
- Samantha R. Eggleston
- Bianca Forsyth
- Pran K. Datta (ORCID: https://orcid.org/0000-0003-2383-2531)
- Hanyu Su (ORCID: https://orcid.org/0009-0007-8608-0687)
- Chi‐Wu Chiang (ORCID: https://orcid.org/0000-0001-6662-157X)
- Parag Das (ORCID: https://orcid.org/0009-0006-0543-6876)
Institutions
- Smith College (US)
- University of Florida Health (US)
- University of Alabama at Birmingham (US)
- University of Florida (US)
- Case Western Reserve University (US)
- National Cheng Kung University (TW)
- Florida College (US)
- Stanford University (US)
Publication Details
- Journal
- Molecular Cancer Research
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1158/1541-7786.mcr-24-0756
- Citations
- 2
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 2.30