DR5 Disulfide Bonding Functions as a Sensor and Effector of Protein Folding Stress

Extreme ER stress triggers triage of transmembrane receptor production, whereby mitogenic receptors are downregulated and death receptors are simultaneously elevated.

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Publication Details

Journal
Molecular Cancer Research
Published
2025-03-19
DOI
https://doi.org/10.1158/1541-7786.mcr-24-0756
Citations
2
Primary Topic
Endoplasmic Reticulum Stress and Disease
Type
article
Field-Weighted Citation Impact
2.30
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article

DR5 Disulfide Bonding Functions as a Sensor and Effector of Protein Folding Stress

Olga A. Guryanova, Gregory P. Takacs, Ronald K. Castellano, Brian K. Law et al.
2 citations
Molecular Cancer Research
Endoplasmic Reticulum Stress and Disease
2.30
article

DR5 Disulfide Bonding Functions as a Sensor and Effector of Protein Folding Stress

Olga A. Guryanova, Gregory P. Takacs, Ronald K. Castellano, Brian K. Law, Jeffrey K. Harrison, Zaafir M. Dulloo, Mary E. Law, Mengxiong Wang, Boaz Tirosh, Raju S. Kanumuri, Brian Hardy, Grace M. Alexandrow, Young Il Lee, Abhisheak Sharma, Samantha R. Eggleston, Bianca Forsyth, Pran K. Datta, Hanyu Su, Chi‐Wu Chiang, Parag Das
article en
2 citations

Abstract

Extreme ER stress triggers triage of transmembrane receptor production, whereby mitogenic receptors are downregulated and death receptors are simultaneously elevated.

Molecular Cancer ResearchVol. 23(7)
Smith College (US), University of Florida Health (US), University of Alabama at Birmingham (US), University of Florida (US), Case Western Reserve University (US), National Cheng Kung University (TW), Florida College (US), Stanford University (US)
Good health and well-being
Openalex Percentile: Top 15%
Endoplasmic Reticulum Stress and Disease
2.30
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DR5 Disulfide Bonding Functions as a Sensor and Effector of Protein Folding Stress — Olga A. Guryanova, Gregory P. Takacs, et al. · Molecular Cancer Research (2025) | TGRS Research Map | TGRS