Construction of ceRNA networks of lncRNA and miRNA associated with intramuscular fat deposition in Ujumqin sheep
Our comprehensive analysis of differentially expressed genes and pathways in Ujumqin sheep's longissimus dorsi and femoral biceps, along with high- and low-IMF groups, has revealed the complex genetics of IMF deposition. This offers valuable resources for Inner Mongolian local breed selection. The interaction between lncRNA MSTRG.13155.1 and miR-1343-3p_R + 2, and their regulation of HADHA expression, provides new insights into IMF deposition mechanisms. Future research can explore these mechanisms' universality and specificity across different breeds and environments.
Authors
- Zhichen Liu
- Chongyan Zhang (ORCID: https://orcid.org/0000-0003-0576-0482)
- Ji An Yang
- Mingxi Lan
- Suhe Alatan
- Ge Zhang (ORCID: https://orcid.org/0000-0002-3116-3246)
- Zhihong Liu (ORCID: https://orcid.org/0000-0001-8639-6306)
- Haijun Zhang (ORCID: https://orcid.org/0000-0002-0236-6482)
- Zhixin Wang (ORCID: https://orcid.org/0000-0003-2383-1010)
- Qing Qin
- Songsong Xu (ORCID: https://orcid.org/0009-0009-6437-9551)
- Xiaolong Xu (ORCID: https://orcid.org/0000-0002-5019-876X)
- Yuchun Xie
Institutions
- Inner Mongolia Agricultural University (CN)
- Hebei Normal University of Science and Technology (CN)
- China Agricultural University (CN)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-03-19
- DOI
- https://doi.org/10.3389/fvets.2025.1559727
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- National Natural Science Foundation of China
- Inner Mongolia Agricultural University