MicrobeRX: a tool for enzymatic-reaction-based metabolite prediction in the gut microbiome
Our analysis revealed both unique and overlapping metabolic capabilities in human and microbial metabolism and chemo- and taxa-specific microbial biotransformations. MicrobeRX bridges the genomic and chemical spaces of the gut microbiome, making it a valuable tool for unlocking the chemical potential of the gut microbiome in human health, the food and pharmaceutical industries, and environmental safety. Video Abstract.
Authors
- Jingyuan Fu (ORCID: https://orcid.org/0000-0001-5578-1236)
- Ángela del Castillo-Izquierdo (ORCID: https://orcid.org/0000-0002-0140-1418)
- Angel J. Ruiz‐Moreno (ORCID: https://orcid.org/0000-0002-2798-5386)
- Isabel Tamargo-Rubio (ORCID: https://orcid.org/0000-0002-0076-2422)
Institutions
- University Medical Center Groningen (NL)
Publication Details
- Journal
- Microbiome
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1186/s40168-025-02070-5
- Citations
- 5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- European Research Council