The IBEX Knowledge-Base: A central resource for multiplexed imaging techniques
Multiplexed imaging is a powerful approach in spatial biology, although it is complex, expensive and labor-intensive. Here, we present the IBEX Knowledge-Base, a central resource for reagents, protocols and more, to enhance knowledge sharing, optimization and innovation of spatial proteomics techniques.
Authors
- Anita Gola (ORCID: https://orcid.org/0000-0003-1431-1398)
- Ian T. Lamborn (ORCID: https://orcid.org/0009-0006-1490-3667)
- Walderez O. Dutra (ORCID: https://orcid.org/0000-0002-7586-9996)
- Megan Vierhout (ORCID: https://orcid.org/0000-0001-5813-2581)
- Annette Oxenius (ORCID: https://orcid.org/0000-0002-2079-2354)
- Vivien I. Maltez (ORCID: https://orcid.org/0000-0003-2330-7518)
- Spencer Fullam (ORCID: https://orcid.org/0000-0001-9012-3802)
- Jake Colautti (ORCID: https://orcid.org/0000-0002-1461-0999)
- Hiroshi Ichise (ORCID: https://orcid.org/0000-0002-5187-810X)
- Kartika Padhan (ORCID: https://orcid.org/0000-0001-9561-4256)
- Kenneth J. Gollob (ORCID: https://orcid.org/0000-0003-4184-3867)
- Nathan Richoz (ORCID: https://orcid.org/0000-0002-7422-3237)
- Edward C. Schrom (ORCID: https://orcid.org/0000-0002-1793-6433)
- Lihong Shi (ORCID: https://orcid.org/0000-0003-4791-4048)
- Rochelle M. Shih (ORCID: https://orcid.org/0000-0002-3218-4479)
- Joshua Croteau (ORCID: https://orcid.org/0000-0002-8142-0482)
- Ryan V. Moriarty (ORCID: https://orcid.org/0000-0001-7100-1906)
- Tibor Z. Veres (ORCID: https://orcid.org/0000-0002-6980-8900)
- Sarah Amalia Teichmann (ORCID: https://orcid.org/0000-0002-6294-6366)
- Yuri Lin (ORCID: https://orcid.org/0009-0006-9784-2694)
- Kirsten Remmert (ORCID: https://orcid.org/0009-0004-0668-4164)
- Jonathan M. Hernandez (ORCID: https://orcid.org/0000-0001-7529-0557)
- Nathan Zangger (ORCID: https://orcid.org/0000-0003-1130-1899)
- Emily Speranza (ORCID: https://orcid.org/0000-0003-0666-4804)
- Wolfgang Kastenmüller (ORCID: https://orcid.org/0000-0002-3835-1485)
- Leanne Arakkal (ORCID: https://orcid.org/0000-0001-9189-7172)
- Andrea J. Radtke (ORCID: https://orcid.org/0000-0003-4379-8967)
- Brianna T. Wachter (ORCID: https://orcid.org/0000-0002-2950-2683)
- Joshua F. E. Koenig (ORCID: https://orcid.org/0000-0002-8909-5039)
- Alexandra Y. Kreins (ORCID: https://orcid.org/0000-0001-8748-5837)
- Evelyn Kandov (ORCID: https://orcid.org/0000-0001-7071-9916)
- Jyh Liang Hor (ORCID: https://orcid.org/0000-0001-6721-4204)
- John E. McDonough (ORCID: https://orcid.org/0000-0003-2497-0258)
- Ryan B. MacDonald (ORCID: https://orcid.org/0000-0003-4194-8925)
- Armando Arroyo-Mejías (ORCID: https://orcid.org/0000-0002-0835-911X)
- Ziv Yaniv (ORCID: https://orcid.org/0000-0003-0315-7727)
- Zhixin Jing (ORCID: https://orcid.org/0000-0003-1118-7432)
- Kátia L.P. Morais (ORCID: https://orcid.org/0000-0001-8877-5887)
- Beatrice Clark (ORCID: https://orcid.org/0009-0003-9817-7874)
- Juan Moisés Ocampo‐Godínez (ORCID: https://orcid.org/0000-0001-5666-4672)
- Rebecca T. Beuschel (ORCID: https://orcid.org/0000-0002-3882-457X)
- Danny Jonigk (ORCID: https://orcid.org/0000-0002-5251-2281)
- Sonja Fritzsche (ORCID: https://orcid.org/0000-0003-3335-3534)
- Ifeanyichukwu U. Anidi (ORCID: https://orcid.org/0000-0002-2692-1225)
- Wanjing Shang (ORCID: https://orcid.org/0009-0007-0646-7946)
- Margaret Williams (ORCID: https://orcid.org/0000-0003-3697-5726)
- Colin J. Chu (ORCID: https://orcid.org/0000-0003-2088-8310)
- Menna Ruth Clatworthy (ORCID: https://orcid.org/0000-0002-3340-9828)
- Michael Y. Gerner (ORCID: https://orcid.org/0000-0001-5406-8308)
- Adam K. Wade‐Vallance (ORCID: https://orcid.org/0000-0002-6863-1461)
- Ronald N. Germain (ORCID: https://orcid.org/0000-0003-1495-9143)
- Fabian Coscia (ORCID: https://orcid.org/0000-0002-2244-5081)
- Aanandita Kothurkar
- Vitoria M Olyntho (ORCID: https://orcid.org/0000-0003-2634-6838)
- Aleksandra Lunich
- Chen Makranz
- Salome Stierli
- Jean CS Luz
- Saven Denha
- Rose Dever
- Katy Börner
- Rosa K Kortekaas
Institutions
- Universidade Federal de Minas Gerais (BR)
- Northwestern University (US)
- Rush University Medical Center (US)
- National Institutes of Health (US)
- Cleveland Clinic (US)
- MRC Laboratory of Molecular Biology (GB)
- Universidade de São Paulo (BR)
- University of Washington (US)
- University of Zurich (CH)
- Max Delbrück Center (DE)
- Wellcome/MRC Cambridge Stem Cell Institute (GB)
- University of Cambridge (GB)
- University of Würzburg (DE)
- Great Ormond Street Hospital (GB)
- Hospital Israelita Albert Einstein (BR)
- Great Ormond Street Hospital for Children NHS Foundation Trust (GB)
- ETH Zurich (CH)
- University of California San Diego (US)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (US)
- NIHR Moorfields Biomedical Research Centre (GB)
- BioLegend (United States) (US)
- Instituto do Câncer do Estado de São Paulo (BR)
- National Heart, Lung, and Blood Institute (US)
- Indiana University Bloomington (US)
- German Center for Lung Research (DE)
- National Institute of Allergy and Infectious Diseases (US)
- National Cancer Institute (US)
- University College London (GB)
- St. Joseph’s Healthcare Hamilton (CA)
- Instituto Politécnico Nacional (MX)
- Rockefeller University (US)
- RWTH Aachen University (DE)
- Universidad Nacional Autónoma de México (MX)
- McMaster University (CA)
Publication Details
- Journal
- PLoS Biology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1371/journal.pbio.3003070
- Citations
- 1
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Damon Runyon Cancer Research Foundation
- Division of Intramural Research, National Institute of Allergy and Infectious Diseases
- Canadian Allergy, Asthma and Immunology Foundation
- NHS Blood and Transplant
- Wellcome Trust
- J.P. Bickell Foundation
- National Institute for Health and Care Research
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Bundesministerium für Bildung und Forschung
- Instituto Politécnico Nacional
- Consejo Nacional de Ciencia y Tecnología
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais
- Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais
- National Institutes of Health
- Canadian Institutes of Health Research
- Biotechnology and Biological Sciences Research Council
- NIHR Cambridge Biomedical Research Centre
- National Institute of General Medical Sciences
- National Institute of Diabetes and Digestive and Kidney Diseases
- Institute of Circulatory and Respiratory Health
- Institute of Infection and Immunity
- Common Fund