The IBEX Knowledge-Base: A central resource for multiplexed imaging techniques

Multiplexed imaging is a powerful approach in spatial biology, although it is complex, expensive and labor-intensive. Here, we present the IBEX Knowledge-Base, a central resource for reagents, protocols and more, to enhance knowledge sharing, optimization and innovation of spatial proteomics techniques.

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Journal
PLoS Biology
Published
2025-03-19
DOI
https://doi.org/10.1371/journal.pbio.3003070
Citations
1
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
0.81

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The IBEX Knowledge-Base: A central resource for multiplexed imaging techniques

Anita Gola, Ian T. Lamborn, Walderez O. Dutra, Megan Vierhout et al.
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The IBEX Knowledge-Base: A central resource for multiplexed imaging techniques

Anita Gola, Ian T. Lamborn, Walderez O. Dutra, Megan Vierhout, Annette Oxenius, Vivien I. Maltez, Spencer Fullam, Jake Colautti, Hiroshi Ichise, Kartika Padhan, Kenneth J. Gollob, Nathan Richoz, Edward C. Schrom, Lihong Shi, Rochelle M. Shih, Joshua Croteau, Ryan V. Moriarty, Tibor Z. Veres, Sarah Amalia Teichmann, Yuri Lin, Kirsten Remmert, Jonathan M. Hernandez, Nathan Zangger, Emily Speranza, Wolfgang Kastenmüller, Leanne Arakkal, Andrea J. Radtke, Brianna T. Wachter, Joshua F. E. Koenig, Alexandra Y. Kreins, Evelyn Kandov, Jyh Liang Hor, John E. McDonough, Ryan B. MacDonald, Armando Arroyo-Mejías, Ziv Yaniv, Zhixin Jing, Kátia L.P. Morais, Beatrice Clark, Juan Moisés Ocampo‐Godínez, Rebecca T. Beuschel, Danny Jonigk, Sonja Fritzsche, Ifeanyichukwu U. Anidi, Wanjing Shang, Margaret Williams, Colin J. Chu, Menna Ruth Clatworthy, Michael Y. Gerner, Adam K. Wade‐Vallance, Ronald N. Germain, Fabian Coscia, Aanandita Kothurkar, Vitoria M Olyntho, Aleksandra Lunich, Chen Makranz, Salome Stierli, Jean CS Luz, Saven Denha, Rose Dever, Katy Börner, Rosa K Kortekaas
article en
1 citations

Abstract

Multiplexed imaging is a powerful approach in spatial biology, although it is complex, expensive and labor-intensive. Here, we present the IBEX Knowledge-Base, a central resource for reagents, protocols and more, to enhance knowledge sharing, optimization and innovation of spatial proteomics techniques.

PLoS BiologyVol. 23(3)
Universidade Federal de Minas Gerais (BR), Northwestern University (US), Rush University Medical Center (US), National Institutes of Health (US), Cleveland Clinic (US), MRC Laboratory of Molecular Biology (GB), Universidade de São Paulo (BR), University of Washington (US), University of Zurich (CH), Max Delbrück Center (DE), Wellcome/MRC Cambridge Stem Cell Institute (GB), University of Cambridge (GB), University of Würzburg (DE), Great Ormond Street Hospital (GB), Hospital Israelita Albert Einstein (BR), Great Ormond Street Hospital for Children NHS Foundation Trust (GB), ETH Zurich (CH), University of California San Diego (US), National Institute of Arthritis and Musculoskeletal and Skin Diseases (US), NIHR Moorfields Biomedical Research Centre (GB), BioLegend (United States) (US), Instituto do Câncer do Estado de São Paulo (BR), National Heart, Lung, and Blood Institute (US), Indiana University Bloomington (US), German Center for Lung Research (DE), National Institute of Allergy and Infectious Diseases (US), National Cancer Institute (US), University College London (GB), St. Joseph’s Healthcare Hamilton (CA), Instituto Politécnico Nacional (MX), Rockefeller University (US), RWTH Aachen University (DE), Universidad Nacional Autónoma de México (MX), McMaster University (CA)
Damon Runyon Cancer Research Foundation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, Canadian Allergy, Asthma and Immunology Foundation, NHS Blood and Transplant, Wellcome Trust, J.P. Bickell Foundation, National Institute for Health and Care Research, Fundação de Amparo à Pesquisa do Estado de São Paulo, Bundesministerium für Bildung und Forschung, Instituto Politécnico Nacional, Consejo Nacional de Ciencia y Tecnología, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Fundação de Amparo à Pesquisa do Estado de Minas Gerais, Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais, National Institutes of Health, Canadian Institutes of Health Research, Biotechnology and Biological Sciences Research Council, NIHR Cambridge Biomedical Research Centre, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, Institute of Circulatory and Respiratory Health, Institute of Infection and Immunity, Common Fund
Industry, innovation and infrastructure
Openalex Percentile: Top 30%
Single-cell and spatial transcriptomics
0.81
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