Persistent Renal Hypoxia and Histologic Changes at 4 Weeks after Cardiopulmonary Bypass in Sheep
Exposure to CPB triggers sustained medullary and cortical tissue hypoxia and is associated with histopathologic renal injury. These findings suggest that the renal effect of exposure to CPB may be more profound and longer lasting than currently appreciated.
Authors
- Connie P. C. Ow (ORCID: https://orcid.org/0000-0001-5402-1809)
- Jai Raman (ORCID: https://orcid.org/0000-0002-7691-4779)
- Rinaldo Bellomo (ORCID: https://orcid.org/0000-0002-1650-8939)
- Roger G. Evans (ORCID: https://orcid.org/0000-0002-9241-0757)
- Yugeesh R. Lankadeva (ORCID: https://orcid.org/0000-0002-3589-9111)
- Clive Newton May (ORCID: https://orcid.org/0000-0001-8548-3846)
- Lachlan Fraser Miles (ORCID: https://orcid.org/0000-0003-2044-5560)
- Anton Lewis Trask-Marino (ORCID: https://orcid.org/0000-0003-4058-8905)
- Ian E. Birchall (ORCID: https://orcid.org/0000-0002-0124-626X)
- Peter McCall (ORCID: https://orcid.org/0000-0003-1209-6882)
- Alemayehu Hailu Jufar (ORCID: https://orcid.org/0009-0000-2669-7836)
- Taku Furukawa (ORCID: https://orcid.org/0000-0001-9898-5802)
- Andrew Donald Cochrane (ORCID: https://orcid.org/0000-0002-2036-013X)
- Bruno Marino (ORCID: https://orcid.org/0000-0002-7392-1615)
- Sally G. Hood
Institutions
- The Royal Melbourne Hospital (AU)
- The University of Melbourne (AU)
- Florey Institute of Neuroscience and Mental Health (AU)
- College of Intensive Care Medicine (AU)
- Australian Regenerative Medicine Institute (AU)
- Australian and New Zealand Intensive Care Society (AU)
- Perfusion Solution (United States) (US)
- Stem Cells Australia (AU)
- Austin Health (AU)
- Monash University (AU)
Publication Details
- Journal
- Anesthesiology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1097/aln.0000000000005452
- Citations
- 7
- Primary Topic
- Cardiac and Coronary Surgery Techniques
- Type
- article
- Field-Weighted Citation Impact
- 14.04