Rationale and Design of ANTHOLOGY: An ATTR Amyloidosis Real-World Evidence Program Aiming to Address Gaps in Amyloidosis Care
ANTHOLOGY aims to broaden understanding of the contemporary epidemiology of ATTR amyloidosis, identify opportunities to accelerate diagnosis, and assess real-world comparative effectiveness of treatments. This knowledge will be used to define world-class patient care, improve treatment outcomes and HRQoL, inform updates to clinical practice guidelines and treatment pathways, and transform ATTR amyloidosis management through evidence aimed at improving the quality of the current standard of care TRIAL REGISTRATION: ClinicalTrials.gov identifier, NCT06355934 (OverTTuRe) and NCT06465810 (MaesTTRo).
Authors
- Zhuang Tian
- J. G. Smith (ORCID: https://orcid.org/0000-0001-6285-9935)
- Eric Wittbrodt (ORCID: https://orcid.org/0000-0002-4060-7638)
- Krister Järbrink (ORCID: https://orcid.org/0000-0003-2612-1233)
- Mia A. Papas (ORCID: https://orcid.org/0000-0001-8636-411X)
- Margot K. Davis (ORCID: https://orcid.org/0000-0001-7367-8267)
- Katrin Hahn (ORCID: https://orcid.org/0000-0002-6013-0072)
- Julian D. Gillmore (ORCID: https://orcid.org/0000-0001-6174-9232)
- Isabel M. Conceição (ORCID: https://orcid.org/0000-0003-0934-9631)
- Christina Pao (ORCID: https://orcid.org/0000-0001-7415-1803)
- Martha Grogan
Institutions
- University of Lisbon (PT)
- University of British Columbia (CA)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sahlgrenska University Hospital (SE)
- The Royal Free Hospital (GB)
- Peking Union Medical College Hospital (CN)
- Mayo Clinic in Arizona (US)
- AstraZeneca (Sweden) (SE)
- Hospital de Santa Maria (PT)
- AstraZeneca (United States) (US)
- University College London (GB)
- Charité - Universitätsmedizin Berlin (DE)
- University of Gothenburg (SE)
Publication Details
- Journal
- Cardiology and Therapy
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1007/s40119-025-00402-y
- Citations
- 3
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- AstraZeneca