A mouse model of sepsis-associated DIC induced by Kappa-carrageenan and Lipopolysaccharides: Establishment and characteristics
This study establishes a standardized mouse model of sepsis-associated DIC using KCG and LPS, which more accurately replicates the key clinical and pathological characteristics of sepsis-associated DIC compared to existing models. This model serves as a novelty and valuable tool for investigating the mechanisms of sepsis-associated DIC and therapeutic evaluation.
Authors
- Yuhui Xie
- Yuying Zheng (ORCID: https://orcid.org/0000-0002-8175-1249)
- Baoqin Lin (ORCID: https://orcid.org/0000-0003-0966-368X)
- Xiubing Zhang (ORCID: https://orcid.org/0009-0000-9147-3089)
- Fangle Liu (ORCID: https://orcid.org/0000-0003-2505-5414)
- Zhongsheng Kuang
- Quan Ou
- Jun Li (ORCID: https://orcid.org/0000-0002-7236-8088)
- Boning Huang
- Ping Tang (ORCID: https://orcid.org/0000-0002-8721-4209)
- Xin-Rong Yang (ORCID: https://orcid.org/0000-0002-7409-6901)
- Bingqing Lin (ORCID: https://orcid.org/0000-0001-9086-0167)
- Huiyi Xie
- Jingjing Sun
- Liuqing Lin
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Shenzhen University (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
- Guangzhou Institute of Dermatology (CN)
- Shenzhen Technology University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1016/j.jare.2025.03.029
- Citations
- 2
- Primary Topic
- Inflammation biomarkers and pathways
- Type
- article
- Field-Weighted Citation Impact
- 1.59