Current insights on the effects of medicinal plants in the management of obesity and infectious diseases: An update from 2020

Medicinal plants have long played a pivotal role in traditional medicine, and their integration into modern healthcare is gaining recognition for their potential in treating a range of conditions, including obesity and infectious diseases. Their bioactive compounds offer a natural, sustainable alternative to synthetic drugs, with significant therapeutic benefits. This review focuses on the recent advances of medicinal plants in addressing two major global health challenges: obesity and infectious diseases. In modern medicine, these plants are valued for their ability to manage weight by influencing metabolic processes such as fat oxidation, insulin sensitivity, and inflammation. Additionally, their antimicrobial properties offer effective solutions against drug-resistant pathogens, presenting a complementary approach to conventional treatments. Through a comprehensive analysis of bioactive compounds, the review investigates their mechanisms, including enzyme inhibition, modulation of immune response, and disruption of microbial growth and biofilm formation. Key findings indicate that these phytochemicals demonstrate both anti-obesity and antimicrobial activities, with potential to reduce inflammation, improve metabolic health, and combat drug-resistant infections. In essence, medicinal plants hold significant promise as natural therapeutic agents for managing obesity and infectious diseases. Their ability to target multiple biological pathways simultaneously makes them effective in addressing the complex interplay between metabolic disorders and immune dysfunction. • Bioactive Compounds in Medicinal Plants can play a role in Obesity and Infectious disease Management. • Molecular Mechanisms of Key Phytochemicals against Disease Progression. • Synergistic combination of key phytochemicals to combat complex diseases including obesity and infectious diseases. • Medicinal plants present a promising complementary solution for managing both obesity and infectious diseases.

Authors

Publication Details

Journal
Aspects of Molecular Medicine
Published
2025-03-19
DOI
https://doi.org/10.1016/j.amolm.2025.100075
Citations
6
Primary Topic
Natural Antidiabetic Agents Studies
Type
article
Field-Weighted Citation Impact
7.77
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article

Current insights on the effects of medicinal plants in the management of obesity and infectious diseases: An update from 2020

O Eric, B. Simeon, Catherine Godson, Onuegbu Chika C. et al.
6 citations
Aspects of Molecular Medicine
Natural Antidiabetic Agents Studies
7.77
article

Current insights on the effects of medicinal plants in the management of obesity and infectious diseases: An update from 2020

O Eric, B. Simeon, Catherine Godson, Onuegbu Chika C., Amafili Chibuzo Collette, Ofoezie Ezichi Favour, Omaba Justina Onyinyechi, Ogbonna Henry Nnaemeka, Ogbonna Chinwendu Angela, George Tiffany Ezinne, Anunobi Chioma Juliet
article en
6 citations

Abstract

Medicinal plants have long played a pivotal role in traditional medicine, and their integration into modern healthcare is gaining recognition for their potential in treating a range of conditions, including obesity and infectious diseases. Their bioactive compounds offer a natural, sustainable alternative to synthetic drugs, with significant therapeutic benefits. This review focuses on the recent advances of medicinal plants in addressing two major global health challenges: obesity and infectious diseases. In modern medicine, these plants are valued for their ability to manage weight by influencing metabolic processes such as fat oxidation, insulin sensitivity, and inflammation. Additionally, their antimicrobial properties offer effective solutions against drug-resistant pathogens, presenting a complementary approach to conventional treatments. Through a comprehensive analysis of bioactive compounds, the review investigates their mechanisms, including enzyme inhibition, modulation of immune response, and disruption of microbial growth and biofilm formation. Key findings indicate that these phytochemicals demonstrate both anti-obesity and antimicrobial activities, with potential to reduce inflammation, improve metabolic health, and combat drug-resistant infections. In essence, medicinal plants hold significant promise as natural therapeutic agents for managing obesity and infectious diseases. Their ability to target multiple biological pathways simultaneously makes them effective in addressing the complex interplay between metabolic disorders and immune dysfunction. • Bioactive Compounds in Medicinal Plants can play a role in Obesity and Infectious disease Management. • Molecular Mechanisms of Key Phytochemicals against Disease Progression. • Synergistic combination of key phytochemicals to combat complex diseases including obesity and infectious diseases. • Medicinal plants present a promising complementary solution for managing both obesity and infectious diseases.

Aspects of Molecular MedicineVol. 5
Zero hunger
Openalex Percentile: Top 3%
Natural Antidiabetic Agents Studies
7.77
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