Miniaturised adaptive optical microscope using compact liquid crystal corrector

Direct Laser Writing in Liquid Crystal (LC) enables a new generation of wavefront shaping devices. By forming polymer structures directly in LC, these devices generate tunable wavefronts using a single electrode pair. The small scale, simplified control, and versatility allows us to bring adaptive optics (AO) to applications previously restricted by device size or complexity. We present a miniaturized AO-enabled microscope with potential for in-vivo mouse brain imaging. By adding a laser-written LC device to our microscope, we can perform full tunable correction of spherical aberration, without the addition of bulky optics or complicated electronics.

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Publication Details

Published
2025-03-19
DOI
https://doi.org/10.1117/12.3042800
Primary Topic
Image Processing Techniques and Applications
Type
article
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Miniaturised adaptive optical microscope using compact liquid crystal corrector

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Image Processing Techniques and Applications
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Miniaturised adaptive optical microscope using compact liquid crystal corrector

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article en

Abstract

Direct Laser Writing in Liquid Crystal (LC) enables a new generation of wavefront shaping devices. By forming polymer structures directly in LC, these devices generate tunable wavefronts using a single electrode pair. The small scale, simplified control, and versatility allows us to bring adaptive optics (AO) to applications previously restricted by device size or complexity. We present a miniaturized AO-enabled microscope with potential for in-vivo mouse brain imaging. By adding a laser-written LC device to our microscope, we can perform full tunable correction of spherical aberration, without the addition of bulky optics or complicated electronics.

University of Oxford (GB)
Affordable and clean energy
Openalex Percentile: Top 93%
Image Processing Techniques and Applications
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