Rare Cases of Escherichia coli-Induced Aortitis in Immunocompromised Patients

Infectious aortitis is a rare, life-threatening condition, with Escherichia coli being an exceptionally uncommon causative pathogen. This case series highlights 2 instances of E coli-induced aortitis in immunocompromised patients, illustrating the clinical challenges and management approaches. The first case involves a 54-year-old man with Waldenstrom macroglobulinemia and recurrent diverticulitis, requiring intravenous antibiotics and endovascular aneurysm repair. The second case features a 66-year-old man with acute myeloid leukemia, successfully managed with antimicrobial therapy alone. These cases underscore the need for early recognition, appropriate imaging, and a multidisciplinary approach for optimal outcomes in E coli-induced infectious aortitis.