Nano-fibre optic probe for label-free bioimaging detection
We present 2D nanomaterial-functionalised fibre optic probes for the bioimaging detection of antibodies. Graphene oxide (GO) provides an ideal platform for biophilic binding interface due to its high surface-to-volume ratio and abundant oxygen functional groups. After functionalisation and bio-immobilisation, the fluorescence images reveal that GO-fibre optic probe exhibits significantly stronger fluorescence intensity compared to bare fibre probes. This GO-fibre optic probe can be further developed as a point-of-care medical device for biomedical imaging and portable bio-detection.
Authors
- Hanlin Jiang
- Mahboobeh Mahmoodi (ORCID: https://orcid.org/0000-0002-9763-6587)
- Xianfeng Chen (ORCID: https://orcid.org/0000-0001-7091-1414)
- Jiaxing Sun (ORCID: https://orcid.org/0000-0001-9901-8187)
Institutions
- Nottingham Trent University (GB)
Publication Details
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1117/12.3041678
- Primary Topic
- Advanced Biosensing Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00