Nano-fibre optic probe for label-free bioimaging detection

We present 2D nanomaterial-functionalised fibre optic probes for the bioimaging detection of antibodies. Graphene oxide (GO) provides an ideal platform for biophilic binding interface due to its high surface-to-volume ratio and abundant oxygen functional groups. After functionalisation and bio-immobilisation, the fluorescence images reveal that GO-fibre optic probe exhibits significantly stronger fluorescence intensity compared to bare fibre probes. This GO-fibre optic probe can be further developed as a point-of-care medical device for biomedical imaging and portable bio-detection.

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Publication Details

Published
2025-03-19
DOI
https://doi.org/10.1117/12.3041678
Primary Topic
Advanced Biosensing Techniques and Applications
Type
article
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article

Nano-fibre optic probe for label-free bioimaging detection

Hanlin Jiang, Mahboobeh Mahmoodi, Xianfeng Chen, Jiaxing Sun
Advanced Biosensing Techniques and Applications
article

Nano-fibre optic probe for label-free bioimaging detection

Hanlin Jiang, Mahboobeh Mahmoodi, Xianfeng Chen, Jiaxing Sun
article en

Abstract

We present 2D nanomaterial-functionalised fibre optic probes for the bioimaging detection of antibodies. Graphene oxide (GO) provides an ideal platform for biophilic binding interface due to its high surface-to-volume ratio and abundant oxygen functional groups. After functionalisation and bio-immobilisation, the fluorescence images reveal that GO-fibre optic probe exhibits significantly stronger fluorescence intensity compared to bare fibre probes. This GO-fibre optic probe can be further developed as a point-of-care medical device for biomedical imaging and portable bio-detection.

Nottingham Trent University (GB)
Openalex Percentile: Top 95%
Advanced Biosensing Techniques and Applications
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