Understanding the nanophotonic chirality transfer with single molecule studies

Chirality transfer in chemistry typically refers to the transfer of stereochemical information between chiral and achiral molecules during molecular interactions. In chiral nanophotonics, this phenomenon is observed when a chiral molecule interacts with a non-chiral resonator, resulting in a resonant shift of the chirality towards that of the resonator. Traditionally, this effect has been widely used for chirality sensing; however, the fundamental mechanisms underlying chirality transfer remain elusive. In this presentation, I will discuss how we leverage single-molecule methods and decoupled optical nanoscopy to interrogate chirality transfer between achiral nanoresonators, chiral resonators, and chiral molecules.

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Publication Details

Published
2025-03-19
DOI
https://doi.org/10.1117/12.3049251
Primary Topic
Advanced Fluorescence Microscopy Techniques
Type
article
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article

Understanding the nanophotonic chirality transfer with single molecule studies

Yang Zhao
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Advanced Fluorescence Microscopy Techniques
article

Understanding the nanophotonic chirality transfer with single molecule studies

Yang Zhao
article en

Abstract

Chirality transfer in chemistry typically refers to the transfer of stereochemical information between chiral and achiral molecules during molecular interactions. In chiral nanophotonics, this phenomenon is observed when a chiral molecule interacts with a non-chiral resonator, resulting in a resonant shift of the chirality towards that of the resonator. Traditionally, this effect has been widely used for chirality sensing; however, the fundamental mechanisms underlying chirality transfer remain elusive. In this presentation, I will discuss how we leverage single-molecule methods and decoupled optical nanoscopy to interrogate chirality transfer between achiral nanoresonators, chiral resonators, and chiral molecules.

University of Illinois System (US)
Openalex Percentile: Top 96%
Advanced Fluorescence Microscopy Techniques
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