High-power compact VCSEL subsystem as game-changer for photoacoustic medical imaging and sensing

We review today's photonic systems (LD/LED/VCSEL/SSL) used for photoacoustic imaging and identify the major challenges to propel this technology into routine clinical use: a factor of 100 in cost, volume, and power consumption for photon generation must be reached. The photonic subsystem presented is based on a compact set-up of triple-junction 940nm and single-junction 850nm VCSEL arrays combined with bare ToF CMOS driver chips. We discuss the optomechanical set-up, the measured key parameters of individual VCSEL arrays and the manufactured VCSEL subsystem with 3.5kW optical peak power for pulse lengths from 10 to 100ns. Even at these high output powers, laser class 1 operation can be achieved. The integrated drivers from automotive LiDAR operate the VCSEL subsystem with a wall-plug efficiency of 25% at a repetition rate of 1kHz. The heat dissipation can be buffered in a small copper block, so the subsystem can directly be mounted within a medical handheld device with no active cooling. We discuss the target applications oxygenation and muscle perfusion for photoacoustic imaging using a combination of 760/800/850nm VCSEL arrays. This VCSEL-based subsystem can replace current photonic systems and is the game-changer for routine clinical use. In addition, the concept is scalable and paves the way towards future patch and sensor photoacoustic applications.

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Publication Details

Published
2025-03-19
DOI
https://doi.org/10.1117/12.3042742
Citations
3
Primary Topic
Spectroscopy and Laser Applications
Type
article
Field-Weighted Citation Impact
2.27
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article

High-power compact VCSEL subsystem as game-changer for photoacoustic medical imaging and sensing

P. Leisching, Christoph Dehner, A. Longo, Dominik Dörich et al.
3 citations
Spectroscopy and Laser Applications
2.27
article

High-power compact VCSEL subsystem as game-changer for photoacoustic medical imaging and sensing

P. Leisching, Christoph Dehner, A. Longo, Dominik Dörich, Alexander Weigl, Guillaume Zahnd, Stephan Gronenborn, Charlène Reichl, Josef Konradl, Cynthia Klett, Uwe Malzahn
article en
3 citations

Abstract

We review today's photonic systems (LD/LED/VCSEL/SSL) used for photoacoustic imaging and identify the major challenges to propel this technology into routine clinical use: a factor of 100 in cost, volume, and power consumption for photon generation must be reached. The photonic subsystem presented is based on a compact set-up of triple-junction 940nm and single-junction 850nm VCSEL arrays combined with bare ToF CMOS driver chips. We discuss the optomechanical set-up, the measured key parameters of individual VCSEL arrays and the manufactured VCSEL subsystem with 3.5kW optical peak power for pulse lengths from 10 to 100ns. Even at these high output powers, laser class 1 operation can be achieved. The integrated drivers from automotive LiDAR operate the VCSEL subsystem with a wall-plug efficiency of 25% at a repetition rate of 1kHz. The heat dissipation can be buffered in a small copper block, so the subsystem can directly be mounted within a medical handheld device with no active cooling. We discuss the target applications oxygenation and muscle perfusion for photoacoustic imaging using a combination of 760/800/850nm VCSEL arrays. This VCSEL-based subsystem can replace current photonic systems and is the game-changer for routine clinical use. In addition, the concept is scalable and paves the way towards future patch and sensor photoacoustic applications.

TRUMPF (Germany) (DE), iThera Medical (Germany) (DE), HausMed (Germany) (DE)
Affordable and clean energy
Openalex Percentile: Top 14%
Spectroscopy and Laser Applications
2.27
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High-power compact VCSEL subsystem as game-changer for photoacoustic medical imaging and sensing — P. Leisching, Christoph Dehner, et al. · (2025) | TGRS Research Map | TGRS