Core-Shell Magnetic Nanocarriers: Fe3O4-Hydroxyapatite/Polysuccinimide Hybrids for Enhanced Oral Bioavailability of Fluorouracil
The current study developed a magnetic targeting nano-delivery system using PSI and Fe/HAP as formulation excipients. The system offers uniform particle size, a simple preparation process, and a cost-effective method for targeted drug delivery. It is not only suitable for liver-targeted drug delivery but also applicable for drug delivery to other tissues in the body for anti-tumor drugs.
Authors
- Fengbo Yu
- Guang-Zhi Shen
- Jinbin Cao (ORCID: https://orcid.org/0000-0002-5637-2976)
- Ying Zhu (ORCID: https://orcid.org/0000-0002-2021-5012)
- Feng‐Guo Zhai
- Fanqin Meng
- Qiang Wang (ORCID: https://orcid.org/0000-0001-7309-9580)
- Wenhui Zhang (ORCID: https://orcid.org/0000-0003-1453-7071)
- Xingjun Fan
Institutions
- Mudanjiang Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/ijn.s507458
- Citations
- 6
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 3.58