Q-switch Tm:YAP laser for dermatology applications

Dermatological lasers are broadly classified as ablative or non-ablative, with laser wavelength as the key difference. Conversely, Thulium lasers at 2 microns primarily coagulate shallow tissues without achieving the ablation threshold due to their intermediate absorption in water. The use of high-energy, passively Q-switched pulses in the nanoseconds regime enables an innovative ablative Tm:YAP laser. This overview show the safety and utility of the ablative thulium laser for medical use. An in vivo study to evaluate the laser safety was conducted on 2 young pig. Veterinarian evaluation of wound healing over 29 days and histopathological results show quick epidermal healing and no signs for adverse effects. An ex vivo experiment was conducted to evaluate the use of thulium ablative laser in laser assisted drug delivery (LADD). The experiment show around 45 times increase in accumulated drug over 6 hours between treated to control samples. These results show that the 1.94 micron Tm:YAP laser, as an innovative addition to the arsenal of ablative lasers, has the potential to revolutionize dermatological practices, providing a safer and reliable solution for diverse skin ailments and treatments.