Assessment of generic corrections for multiview Cherenkov emission during total skin electron therapy (TSET)

Cherenkov imaging is a valuable tool for quality assurance of dose homogeneity in total skin electron therapy (TSET), where patients are treated in six postures using the Stanford technique. Cherenkov signals emitted from the patient's surface are captured, corrected, converted into 2D dose maps, and projected onto the body to generate a 3D pseudo dose distribution. This study aims to improve the accuracy of Cherenkov-converted doses by applying patient-specific generic correction factors derived from Monte Carlo simulations using finite element meshes (FEMs) reconstructed from 3D scans. A clinical study involving eight patients compared the corrected Cherenkov dose with in-vivo dosimetry (IVD) measurements. After applying generic corrections, the Cherenkov-converted dose showed good agreement with IVD, particularly in the shins, with discrepancies within 10%.