Deciphering the Pharmacological Potential of Kouqiangjie Formula for the Treatment of Diabetic Periodontitis Based on Network Pharmacology, Machine Learning, Molecular Dynamics, and Animal Experiments
In summary, KQJF exhibits potential therapeutic benefits for DP through a multi-component and multi-target approach, potentially offering a novel integrative treatment strategy. This study underscores the importance of integrating traditional medicine with modern molecular techniques to explore novel therapeutic avenues for complex comorbid conditions, providing a blueprint for future pharmacological explorations.
Authors
- Lixing Zhao (ORCID: https://orcid.org/0000-0002-9870-6436)
- Jing Wei (ORCID: https://orcid.org/0000-0003-1062-6691)
- Min Liu (ORCID: https://orcid.org/0000-0001-7076-5066)
- Ranran Gao (ORCID: https://orcid.org/0000-0002-7164-0289)
- Huijing Li (ORCID: https://orcid.org/0009-0004-3618-761X)
- Yeke Wu
- Yunfei Xie (ORCID: https://orcid.org/0000-0002-7831-8196)
- Jiawei Li (ORCID: https://orcid.org/0000-0001-9968-9124)
- Qiongying Hu
- Li Li
Institutions
- University of Electronic Science and Technology of China (CN)
- Sichuan University (CN)
- Henan Provincial People's Hospital (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/dddt.s494066
- Citations
- 2
- Primary Topic
- Traditional Chinese Medicine Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.76