Performance of an Intravascular Tantalum Oxide–Based Nanoparticle Computed Tomography Contrast Agent in Preclinical Hepatic Tumor Detection
Experimental TaCZ nanoparticles showed higher hepatic contrast enhancement and improved the detection and conspicuity of hepatic tumors at all sizes and scan delays compared to iopamidol, with sustained intense contrast enhancement in delayed venous phase up to at least 180 seconds.
Authors
- Michael Ingrisch (ORCID: https://orcid.org/0000-0003-0268-9078)
- Peter J. Bonitatibus (ORCID: https://orcid.org/0000-0002-6650-9059)
- Cheng William Hong (ORCID: https://orcid.org/0000-0002-5219-6039)
- Nikki Okwelogu
- Brian C. Bales
- Johanna Luitjens
- Sina Houshmand (ORCID: https://orcid.org/0000-0002-8935-6622)
- Yuxin Sun (ORCID: https://orcid.org/0000-0001-8060-3693)
- Benjamin M. Yeh (ORCID: https://orcid.org/0000-0003-2174-3009)
- Theresia Aschauer
- Maurice M. Heimer (ORCID: https://orcid.org/0000-0002-0940-0161)
- Dan E. Meyer (ORCID: https://orcid.org/0000-0002-1574-1704)
- Clemens C. Cyran (ORCID: https://orcid.org/0000-0001-5630-6242)
Institutions
- Maharaja Yeshwantrao Hospital (IN)
- LMU Klinikum (DE)
- Dwight Englewood School (US)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Investigative Radiology
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1097/rli.0000000000001175
- Citations
- 2
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 2.72