A case report on an aggressive form of squamous cell carcinoma in the left side of maxillary alveolus

Rationale: Worldwide, malignancy of the oral cavity is among the sixth leading cause of neoplasm, and India occupied second place in the highest number of cancer prevalence. The carcinogenesis of oral squamous cell carcinoma (OSCC) is a multistage process, associated with tobacco usage, alcohol, human papillomavirus, Epstein–Barr virus, immune, and nutritional deficiency. Tobacco usage was found to be the main culprit having >60 harmful substances that invariably produce epigenetic changes in oral epithelial cells. Maxillary alveolar tumors are usually uncommon and biologically more aggressive than various places in the oral cavity because of complex anatomy and early invasion of the infratemporal fossa. OSCC may manifest as many histopathological of these distinctions constitute between 10% and 15% worldwide carcinomas involving the squamous cells. Diagnosis: The present case is histologically consistent with the vital diagnostic qualities of basaloid versions of carcinoma of squamous cells. Intervention: Treatment option of neoadjuvant chemotherapy along with wide surgical excision followed by bilateral radical neck dissection up to Level I–IV lymph node was suggested. But unfortunately, the patient was not willing and not fit for the surgical management. Conclusion: Basaloid squamous cell carcinoma is a sporadic and malignant sort of oral carcinoma which usually appears with high-grade ailments and a dismal prognosis. Mortality rates vary depending with the phase of the illness at the moment of assessment. This depicts the role of healthcare experts to prevent this disease by altering lifestyle modification and early diagnosis which could reduce the incidence percentage and also increase the lifespan longevity of humans.

Authors

Institutions

Publication Details

Journal
SRM Journal of Research in Dental Sciences
Published
2025-01-01
DOI
https://doi.org/10.4103/srmjrds.srmjrds_93_24
Primary Topic
Oral and Maxillofacial Pathology
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A case report on an aggressive form of squamous cell carcinoma in the left side of maxillary alveolus

Santha Devy Arumugam, Sivaramakrishnan Muthanandam, Umamaheswari Giri, Veeramuthulingam Nagarajan et al.
SRM Journal of Research in Dental Sciences
Oral and Maxillofacial Pathology
article

A case report on an aggressive form of squamous cell carcinoma in the left side of maxillary alveolus

Santha Devy Arumugam, Sivaramakrishnan Muthanandam, Umamaheswari Giri, Veeramuthulingam Nagarajan, Vidyalakshmi Santhanam, A. Ijjas Fahi
article en

Abstract

Rationale: Worldwide, malignancy of the oral cavity is among the sixth leading cause of neoplasm, and India occupied second place in the highest number of cancer prevalence. The carcinogenesis of oral squamous cell carcinoma (OSCC) is a multistage process, associated with tobacco usage, alcohol, human papillomavirus, Epstein–Barr virus, immune, and nutritional deficiency. Tobacco usage was found to be the main culprit having >60 harmful substances that invariably produce epigenetic changes in oral epithelial cells. Maxillary alveolar tumors are usually uncommon and biologically more aggressive than various places in the oral cavity because of complex anatomy and early invasion of the infratemporal fossa. OSCC may manifest as many histopathological of these distinctions constitute between 10% and 15% worldwide carcinomas involving the squamous cells. Diagnosis: The present case is histologically consistent with the vital diagnostic qualities of basaloid versions of carcinoma of squamous cells. Intervention: Treatment option of neoadjuvant chemotherapy along with wide surgical excision followed by bilateral radical neck dissection up to Level I–IV lymph node was suggested. But unfortunately, the patient was not willing and not fit for the surgical management. Conclusion: Basaloid squamous cell carcinoma is a sporadic and malignant sort of oral carcinoma which usually appears with high-grade ailments and a dismal prognosis. Mortality rates vary depending with the phase of the illness at the moment of assessment. This depicts the role of healthcare experts to prevent this disease by altering lifestyle modification and early diagnosis which could reduce the incidence percentage and also increase the lifespan longevity of humans.

SRM Journal of Research in Dental SciencesVol. 16(1)
Sri Balaji Vidyapeeth University (IN)
Openalex Percentile: Top 93%
Oral and Maxillofacial Pathology
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

A case report on an aggressive form of squamous cell carcinoma in the left side of maxillary alveolus — Santha Devy Arumugam, Sivaramakrishnan Muthanandam, et al. · SRM Journal of Research in Dental Sciences (2025) | TGRS Research Map | TGRS