Neutrophil gelatinase-associated lipocalin levels are associated with skin thickness and metabolic syndrome features in patients with systemic sclerosis

NGAL serum levels in patients with SSc correlate positively and independently with extension of the skin involvement. NGAL levels also correlate with features of metabolic syndrome, such as a dyslipidaemic pattern and reduced insulin sensitivity, which may be associated with an increased risk of atherosclerosis and cardiovascular disease in patients with SSc.

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Publication Details

Journal
Clinical and Experimental Rheumatology
Published
2024-08-12
DOI
https://doi.org/10.55563/clinexprheumatol/lad3qd
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Neutrophil gelatinase-associated lipocalin levels are associated with skin thickness and metabolic syndrome features in patients with systemic sclerosis

Mónica Renuncio‐García, Iván Ferraz‐Amaro, Santos Castañeda, Miguel Ángel González-Gay et al.
Clinical and Experimental Rheumatology
Systemic Sclerosis and Related Diseases
article

Neutrophil gelatinase-associated lipocalin levels are associated with skin thickness and metabolic syndrome features in patients with systemic sclerosis

Mónica Renuncio‐García, Iván Ferraz‐Amaro, Santos Castañeda, Miguel Ángel González-Gay, Javier Gonzalo Ocejo-Vinyals, Esther F. Vicente‐Rabaneda, Zena Ibrahim-Achi, Antonia de Vera-González
article en

Abstract

NGAL serum levels in patients with SSc correlate positively and independently with extension of the skin involvement. NGAL levels also correlate with features of metabolic syndrome, such as a dyslipidaemic pattern and reduced insulin sensitivity, which may be associated with an increased risk of atherosclerosis and cardiovascular disease in patients with SSc.

Clinical and Experimental RheumatologyVol. 43(8)
Universidad de La Laguna (ES), Hospital Universitario de Canarias (ES), Instituto de Investigación Marqués de Valdecilla (ES), Hospital Universitario Fundación Jiménez Díaz (ES), Hospital Universitario de La Princesa (ES)
Pfizer, Sanofi, Celgene, European Commission, Instituto de Salud Carlos III
Openalex Percentile: Top 59%
Systemic Sclerosis and Related Diseases
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Neutrophil gelatinase-associated lipocalin levels are associated with skin thickness and metabolic syndrome features in patients with systemic sclerosis — Mónica Renuncio‐García, Iván Ferraz‐Amaro, et al. · Clinical and Experimental Rheumatology (2024) | TGRS Research Map | TGRS