Genetic insights into blood urea nitrogen as a risk factor for coronary artery disease: a Mendelian randomization study in East Asians
This MR work shows that elevated BUN levels are a potential biomarker for CAD risk but lack causal associations with other CVDs. These findings suggest avenues for risk stratification and CAD prevention strategies, emphasizing the clinical utility of BUN monitoring in at-risk populations.
Authors
- Zhouqing Huang (ORCID: https://orcid.org/0000-0001-5854-1377)
- Qianxin Zhang
- Lijuan Shen (ORCID: https://orcid.org/0000-0001-7470-9432)
- Zhouyang Zhu
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Jiaxing University (CN)
- Yuxian People's Hospital (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1080/0886022x.2025.2477318
- Citations
- 2
- Primary Topic
- Peroxisome Proliferator-Activated Receptors
- Type
- article
- Field-Weighted Citation Impact
- 1.61