Comparative analysis of the oral cavity microflora state in various degrees of inflammatory conditions of periodontal tissues using comprehensive studies

The authors conducted a comparative analysis of the frequency of occurrence of various bacterial pathogens in the oral cavity (OC) and their role in the etiology of periodontal complex diseases in patients with periodontitis of varying severity and a control group (CG) of healthy individuals. The study results demonstrated that significant changes in the periodontal complex microflora were more frequently observed in individuals with various inflammatory periodontal diseases. These changes were detected using classical and modern methods to study the composition of the microflora of the oral mucosa (OM) and gums. The findings showed an increase in both periodontopathogenic agents and pathogenic coccal flora. According to the authors, the combination of microorganisms from the "red complex" with Streptococcus pyogenes and Staphylococcus aureus contributes to biofilm formation and a higher risk of exopolymeric matrix destruction, which corresponds to the clinical manifestations and severity of periodontitis progression.