Satellite DNA Amplification in Advanced Prostate Cancer Is Largely Independent From Euchromatic and Oncogene Amplicons
Recently, we were able to show that satellite DNA amplification (satDNA-AMP) is present in advanced prostate cancer. A chromosome microarray study provided first evidence that satDNA-AMP appears to be largely independent of centromere-near/pericentric euchromatic copy number alterations. Therefore, it might be carefully suggested that satDNA-AMP could be a new and independent marker for advanced tumor progression.
Authors
- Antônio Augusto Ornellas (ORCID: https://orcid.org/0000-0002-6497-511X)
- Jessica Holler
- Thomas Liehr (ORCID: https://orcid.org/0000-0003-1672-3054)
- Gilda Alves (ORCID: https://orcid.org/0000-0003-2246-719X)
- Melanie Wolter (ORCID: https://orcid.org/0009-0001-0428-4341)
- Bernhard Theis
- Anja Weise (ORCID: https://orcid.org/0000-0003-3988-8919)
- Elena Jamali (ORCID: https://orcid.org/0000-0001-5536-9727)
- Constanze Pentzold (ORCID: https://orcid.org/0000-0003-3711-8945)
Institutions
- Universidade do Estado do Rio de Janeiro (BR)
- Hospital Estadual Mário Covas (BR)
- Jena University Hospital (DE)
- Friedrich Schiller University Jena (DE)
Publication Details
- Journal
- Journal of Histochemistry & Cytochemistry
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1369/00221554251323657
- Citations
- 2
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 1.87