Risk for Unplanned Pregnancy Among Survivors of Childhood Cancer

The purpose of this study was to identify factors associated with risk for unplanned pregnancy in sexually active female survivors using self-report survey data. Risk for unplanned pregnancy was defined as using less effective/no contraception while also not desiring pregnancy. Of N = 160 participants (age 24.0 ± 3.1 years), 33.1% were at-risk for unplanned pregnancy. On multivariable analysis, participants were less likely to be categorized at-risk for unplanned pregnancy if they reported diagnosis of ovarian failure/premature menopause (odds ratio [OR] 0.16, 95% confidence interval [CI] 0.02-0.72, p = 0.032), greater concerns about fertility (OR 0.59, 95%CI 0.43-0.80, p = 0.001), and religious identity of agnostic/atheist (compared with Christian, OR 0.10, 95%CI 0.01-0.41, p = 0.005).

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2025-03-17
DOI
https://doi.org/10.1002/pbc.31653
Primary Topic
Assisted Reproductive Technology and Twin Pregnancy
Type
article
Field-Weighted Citation Impact
0.00

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article

Risk for Unplanned Pregnancy Among Survivors of Childhood Cancer

Holly Hoefgen, Kate Fitch, Brooke Cherven, Jenna Demedis et al.
Pediatric Blood & Cancer
Assisted Reproductive Technology and Twin Pregnancy
article

Risk for Unplanned Pregnancy Among Survivors of Childhood Cancer

Holly Hoefgen, Kate Fitch, Brooke Cherven, Jenna Demedis, James L. Klosky, Karen Burns, Luke Esposito, Ann C. Mertens, Ebonee Harris
article en

Abstract

The purpose of this study was to identify factors associated with risk for unplanned pregnancy in sexually active female survivors using self-report survey data. Risk for unplanned pregnancy was defined as using less effective/no contraception while also not desiring pregnancy. Of N = 160 participants (age 24.0 ± 3.1 years), 33.1% were at-risk for unplanned pregnancy. On multivariable analysis, participants were less likely to be categorized at-risk for unplanned pregnancy if they reported diagnosis of ovarian failure/premature menopause (odds ratio [OR] 0.16, 95% confidence interval [CI] 0.02-0.72, p = 0.032), greater concerns about fertility (OR 0.59, 95%CI 0.43-0.80, p = 0.001), and religious identity of agnostic/atheist (compared with Christian, OR 0.10, 95%CI 0.01-0.41, p = 0.005).

Pediatric Blood & CancerVol. 72(6)
Cincinnati Children's Hospital Medical Center (US), WellStar Health System (US), Emory University (US), Washington University in St. Louis (US), Children's Hospital Colorado (US), Center for Cancer and Blood Disorders (US), Aflac (United States) (US), Children's Healthcare of Atlanta (US), University of Cincinnati Medical Center (US), University of Colorado Denver (US)
National Institutes of Health
Good health and well-being
Openalex Percentile: Top 93%
Assisted Reproductive Technology and Twin Pregnancy
DOIOpen Access PDFOpenAlex
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Risk for Unplanned Pregnancy Among Survivors of Childhood Cancer — Holly Hoefgen, Kate Fitch, et al. · Pediatric Blood & Cancer (2025) | TGRS Research Map | TGRS