Whole‐genome CRISPR‐Cas9 knockout screens identify <i>SHOC2</i> as a genetic dependency in <i>NRAS</i> ‐mutant melanoma

Authors

Andrea Y. Gu
Francis W. Hunter (ORCID: https://orcid.org/0000-0002-9970-8679)
Dean C. Singleton (ORCID: https://orcid.org/0000-0002-2044-8078)
Xuenan Zhang (ORCID: https://orcid.org/0000-0002-7072-2784)
Tet Woo Lee (ORCID: https://orcid.org/0000-0002-2744-1784)
Stephen M. F. Jamieson (ORCID: https://orcid.org/0000-0002-5485-9211)
Aziza Khan (ORCID: https://orcid.org/0000-0001-9496-3104)

Institutions

Johnson & Johnson (United States) (US)
University of Auckland (NZ)
Cancer Society of New Zealand (NZ)
Maurice Wilkins Centre (NZ)
Johnson & Johnson (Israel) (IL)

Publication Details

Journal: Cancer Communications
Published: 2025-03-17
DOI: https://doi.org/10.1002/cac2.70013
Citations: 2
Primary Topic: Melanoma and MAPK Pathways
Type: article
Field-Weighted Citation Impact: 1.61

Funders

Cancer Society of New Zealand
Cancer Research Trust New Zealand

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article

Whole‐genome CRISPR‐Cas9 knockout screens identify SHOC2 as a genetic dependency in NRAS ‐mutant melanoma

Andrea Y. Gu, Francis W. Hunter, Dean C. Singleton, Xuenan Zhang et al.

Mar 17, 2025

2 citations

Cancer Communications

Melanoma and MAPK Pathways

1.61

article

Whole‐genome CRISPR‐Cas9 knockout screens identify SHOC2 as a genetic dependency in NRAS ‐mutant melanoma

Andrea Y. Gu, Francis W. Hunter, Dean C. Singleton, Xuenan Zhang, Tet Woo Lee, Stephen M. F. Jamieson, Aziza Khan

March 17, 2025article en

2 citations

Abstract

No abstract available for this paper.

Cancer CommunicationsVol. 45(6)

Johnson & Johnson (United States) (US), University of Auckland (NZ), Cancer Society of New Zealand (NZ), Maurice Wilkins Centre (NZ), Johnson & Johnson (Israel) (IL)

Cancer Society of New Zealand, Cancer Research Trust New Zealand

Zero hunger

Openalex Percentile: Top 18%

Melanoma and MAPK Pathways

1.61

DOI Open Access PDF OpenAlex

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