Macrophage Membrane Coated Manganese Dioxide Nanoparticles Loaded with Rapamycin Alleviate Intestinal Ischemia-Reperfusion Injury by Reducing Oxidative Stress and Enhancing Autophagy
Our results demonstrated that Ma@(MnO₂+RAPA) alleviated intestinal I/R injury by reducing oxidative stress, promoting autophagy, and inhibiting inflammation. This study offers a potential therapeutic strategy for the treatment of intestinal ischemia-reperfusion injury.
Authors
- Bin Li (ORCID: https://orcid.org/0000-0001-9870-9963)
- Ying Wang (ORCID: https://orcid.org/0000-0002-7409-3794)
- Ren Sheng (ORCID: https://orcid.org/0000-0002-2293-8986)
- Weian Zeng (ORCID: https://orcid.org/0000-0002-6783-2245)
- Yuhui Liao (ORCID: https://orcid.org/0000-0003-4702-9516)
- Xuan Li (ORCID: https://orcid.org/0000-0001-6319-3020)
- Wei Wang (ORCID: https://orcid.org/0000-0001-6593-5016)
- Yong Liang (ORCID: https://orcid.org/0000-0003-2212-6694)
- Dezhao Liu (ORCID: https://orcid.org/0000-0002-0422-5464)
- Haoyuan Yu
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Southern Medical University (CN)
- Fifth Affiliated Hospital of Sun Yat-sen University (CN)
- Ningxia Medical University (CN)
- Sun Yat-sen University Cancer Center (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/ijn.s507546
- Citations
- 7
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 10.30