Prospective Study to Assess Long‐Term Outcomes of Chelator‐Based Treatment With Trientine Dihydrochloride in Patients With Wilson Disease

This study demonstrated that treatment with TETA-2HCl was effective and well tolerated in hepatic and neurologic disease manifestations. Additionally, improvement in neurological symptoms was reported throughout the trial, suggesting that improvements may be reported for an extended period after initiation of therapy. <b>Trial Registration:</b> NCT02426905.

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Publication Details

Journal
JGH Open
Published
2025-03-01
DOI
https://doi.org/10.1002/jgh3.70114
Primary Topic
Trace Elements in Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Prospective Study to Assess Long‐Term Outcomes of Chelator‐Based Treatment With Trientine Dihydrochloride in Patients With Wilson Disease

Karl Heinz Weiss, Isabelle Mohr, Verena Aliane, Carlot Kruse
JGH Open
Trace Elements in Health
article

Prospective Study to Assess Long‐Term Outcomes of Chelator‐Based Treatment With Trientine Dihydrochloride in Patients With Wilson Disease

Karl Heinz Weiss, Isabelle Mohr, Verena Aliane, Carlot Kruse
article en

Abstract

This study demonstrated that treatment with TETA-2HCl was effective and well tolerated in hepatic and neurologic disease manifestations. Additionally, improvement in neurological symptoms was reported throughout the trial, suggesting that improvements may be reported for an extended period after initiation of therapy. <b>Trial Registration:</b> NCT02426905.

JGH OpenVol. 9(3)
Heidelberg University (DE), University Hospital Heidelberg (DE), Krankenhaus Salem (DE)
Good health and well-being
Openalex Percentile: Top 94%
Trace Elements in Health
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