From Breast to Eye: A Rare Case of Ocular Metastasis From Luminal Breast Cancer in a Nicaraguan Patient

Ocular metastases from breast cancer are rare but significant, with invasive lobular carcinoma (ILC) showing a higher tendency for ocular involvement than invasive ductal carcinoma (IDC). Radiotherapy is the main treatment, but the prognosis is poor. This case involves a 37-year-old woman with a history of bilateral breast cancer, initially treated with surgery, chemotherapy, and radiotherapy. She later developed pulmonary progression, bone metastases, and other complications. The patient experienced worsening vision loss, headaches, tinnitus, and systemic decline. Imaging showed brain lesions and choroidal metastasis. Extensive metastasis was confirmed, including in the pleura, liver, and bones. Ophthalmologic evaluation revealed increased intraocular pressure, requiring medical management and planned cyclophotocoagulation. Due to the advanced disease, a palliative care approach was initiated, with radiotherapy planned for ocular metastasis. This case highlights the aggressive nature of metastatic luminal B breast cancer with ocular involvement and underscores the importance of early detection and a multidisciplinary approach to patient care.

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Publication Details

Journal
Cureus
Published
2025-03-17
DOI
https://doi.org/10.7759/cureus.80748
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

From Breast to Eye: A Rare Case of Ocular Metastasis From Luminal Breast Cancer in a Nicaraguan Patient

Gilberto A Altamirano, Lorenzo E Aragón Conrado, Christopher Romero, Catherine S Moreno Cabrera et al.
Cureus
Ocular Oncology and Treatments
article

From Breast to Eye: A Rare Case of Ocular Metastasis From Luminal Breast Cancer in a Nicaraguan Patient

Gilberto A Altamirano, Lorenzo E Aragón Conrado, Christopher Romero, Catherine S Moreno Cabrera, Johanna I Sobalvarro
article en

Abstract

Ocular metastases from breast cancer are rare but significant, with invasive lobular carcinoma (ILC) showing a higher tendency for ocular involvement than invasive ductal carcinoma (IDC). Radiotherapy is the main treatment, but the prognosis is poor. This case involves a 37-year-old woman with a history of bilateral breast cancer, initially treated with surgery, chemotherapy, and radiotherapy. She later developed pulmonary progression, bone metastases, and other complications. The patient experienced worsening vision loss, headaches, tinnitus, and systemic decline. Imaging showed brain lesions and choroidal metastasis. Extensive metastasis was confirmed, including in the pleura, liver, and bones. Ophthalmologic evaluation revealed increased intraocular pressure, requiring medical management and planned cyclophotocoagulation. Due to the advanced disease, a palliative care approach was initiated, with radiotherapy planned for ocular metastasis. This case highlights the aggressive nature of metastatic luminal B breast cancer with ocular involvement and underscores the importance of early detection and a multidisciplinary approach to patient care.

CureusVol. 17(3)
Military Hospital (PK), Central Military Hospital (NL)
Good health and well-being
Openalex Percentile: Top 91%
Ocular Oncology and Treatments
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