Twin-To-Twin Transfusion Syndrome (Ttts) Associated With Single Intrauterine Fetal Death: Report Of A Clinical Case

Approximately 20–25% of twin pregnancies are monochorionic, meaning that the twins share a single placenta.1 Out of these monochorionic twin pregnancies, about 10–15% are complicated by twin-to-twin transfusion syndrome (TTTS), which arises from unequal sharing of the placental blood supply. TTTS generally manifests during the second trimester of pregnancy, most commonly between 16 and 26 weeks. It occurs due to the net transfer of fluids and hormones from one twin to the other through vascular connections on the placenta. If left untreated, TTTS can have a very poor prognosis. While stage I of the condition may stabilize or even improve in up to 30% of cases managed with observation, there is a risk of progression, fetal demise, or previable birth.