The Role of the Major Histocompatibility Complex Region on Chromosome 6 in Skin Atrophy: A Mendelian Randomization Study
This study highlights the involvement of six core genes within the MHC region on chromosome 6 in the development of SA, emphasizing their roles in immune regulation and antigen presentation. These findings open new avenues for understanding SA and offer a foundation for future investigations into immune-related pathways in skin diseases.
Authors
- Ziwen Fan (ORCID: https://orcid.org/0000-0002-1050-3483)
- Wenyang Li (ORCID: https://orcid.org/0000-0001-6078-6357)
- Yuehang Sun
- Chenyu Zhao (ORCID: https://orcid.org/0009-0007-9490-2062)
- Ruihan Zhang (ORCID: https://orcid.org/0000-0002-7350-1370)
Institutions
- Queen's University Belfast (GB)
- First Hospital of China Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Journal of Cosmetic Dermatology
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1111/jocd.70040
- Citations
- 2
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- National Natural Science Foundation of China