Chromium catalyzed acceptorless dehydrogenative (cross)coupling of primary amines to secondary imines
We present here acceptorless dehydrogenative coupling of primary amines to form secondary aldimines catalyzed by a complex of Earth-abundant chromium. The reaction is promoted by Cr(DAFO)(CO)<sub>4</sub> (DAFO = 4,5-diazafluorene-9-one) without using any additives, base or oxidant generating NH<sub>3</sub> and H<sub>2</sub> as sole by-products. Dehydrogenative cross-coupling of primary amines with aniline derivatives to unsymmetrical secondary imines was also achieved with good to excellent yields. A probable mechanism is proposed based on the stoichiometric investigation and computational studies.
Authors
- Sachin Jalwal (ORCID: https://orcid.org/0000-0003-1788-3404)
- Debangsu Sil (ORCID: https://orcid.org/0000-0002-0718-3925)
- Manikandan Paranjothy (ORCID: https://orcid.org/0000-0002-4126-6206)
- Aman Anand (ORCID: https://orcid.org/0000-0001-8984-1663)
- Subrata Chakraborty (ORCID: https://orcid.org/0000-0002-0174-2095)
- Anitta Regina
- Soumojyati Prodhan
Institutions
- Indian Institute of Technology Jodhpur (IN)
- Indian Institute of Science Education and Research Pune (IN)
Publication Details
- Journal
- Dalton Transactions
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d4dt03460k
- Citations
- 5
- Primary Topic
- Asymmetric Hydrogenation and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 2.69