Interleukin 8 as a Causal Link Between Aging and Impaired Influenza Antibody Responses in Older Adults
Our findings underscore IL-8 as a potential mediator of antibody responses to influenza vaccination in older adults, suggesting that IL-8 inhibition could serve as a molecular intervention to improve antibody responses in this high-risk population.
Authors
- Huy Quang Quach (ORCID: https://orcid.org/0000-0003-2191-5771)
- Inna G. Ovsyannikova (ORCID: https://orcid.org/0000-0003-1506-9214)
- Richard B. Kennedy
- Diane E. Grill (ORCID: https://orcid.org/0000-0002-8677-1724)
- Gregory A. Poland (ORCID: https://orcid.org/0000-0001-5057-4457)
- Krista M. Goergen
Institutions
- New York Academy of Medicine (US)
- Mayo Clinic (US)
- New York Academy of Sciences (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1093/infdis/jiaf148
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00