Giant natal cleft epidermal inclusion cyst surgically excised in a young male in Australia

Epidermal inclusion cysts are benign lesions commonly found in hair-bearing areas. Giant epidermal inclusion cysts (GEICs), those exceeding 5 cm in diameter, are rare and may pose diagnostic challenges, especially in atypical locations. We report the case of a 29-year-old male with a 7-8 cm swelling in the natal cleft, diagnosed as a GEIC after imaging studies, including ultrasound, CT, and MRI. Surgical excision was performed with careful dissection to preserve surrounding structures. The patient had an uneventful recovery. This case highlights the diagnostic and surgical challenges of GEICs in the natal cleft and emphasizes the importance of pre-operative imaging and meticulous surgical technique to avoid complications.